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Obesity appears to
increase the possibility of prevalent vertebral fracture (VF) in both men and
women.
According to a recent cross-sectional analysis published in the Journal of Osteoporosis International, obese people show a higher absolute bone mineral density (BMD) which is disproportionate to body weight, and this may partially describe the higher vertebral fracture (VF) prevalence. Obesity is known as a global epidemic. However, the relationship between obesity and osteoporosis is yet not clear. This cross-sectional study focused on to assess the associations of obesity and BMI with BMD and prevalent VF within men and women aged 62 years. A total of 342 males and females from Newcastle Thousand Families Study birth cohort selected and went through DXA assessments of the lumbar spine, femoral neck and lateral spine BMD for vertebral fracture evaluation.
As compared to
women, men showed a higher possibility of prevalent VF. Among women, the
probability of prevalent any-grade VF raised as the BMI increased. Obese women
found to more prone to at least one grade 1 vertebral deformity and one VF as
compared to normal-weight women and obese men as compared to normal-weight men
were more prone to grade 2 and/or grade 3 VF. The BMI found to associate
negatively to lumbar spine BMD/weight and femoral neck BMD/weight. Obese people
showed low BMD when displayed relative to body weight; however, absolute BMD
increases in obesity; this may not be equivalent to enhanced body mass and fat
mass. As the obesity rates are rising, distant and timely research is required
to assess the correlation between BMD/weight and vertebral fracture risk.
Osteoporos Int.
Obesity, bone density relative to body weight and prevalent vertebral fracture at age 62 years: the Newcastle thousand families study.
H. A. Rudman et al.
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