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In chronic obstructive pulmonary disease patients, there is a higher risk for irritable bowel syndrome, functional dyspepsia, and gastroesophageal reflux disease.
A recent study published in Respiratory Medicine revealed a greater risk of functional gastrointestinal disorders (FGIDs) in people with chronic obstructive pulmonary disorder (COPD).
To explore the relationship between COPD and future FGIDs development, Yu-Chi Chiu et al. conducted a nationwide population-based study.
Overall, 4107 subjects were included in the COPD cohort and 12,321 gender- and age-matched subjects without COPD were randomly selected for a comparison cohort. For five years, both cohorts were examined for the incidence of FGIDs. The validation study substantiated the accuracy of COPD definitions.
The adjusted hazard ratios (aHR) of FGIDs were greater in the COPD cohort when compared to the comparison cohort. COPD patients had a higher risk for irritable bowel syndrome (aHR: 1.55), gastroesophageal reflux disease (aHR: 2.10), and functional dyspepsia (aHR: 1.34). Compared to the unvalidated COPD group, the validated COPD group exhibited consistent results. Hence, people with COPD are more susceptible to develop FGIDs.
Respiratory Medicine
Chronic obstructive pulmonary disease is associated with a higher risk of functional gastrointestinal disorders
Yu-Chi Chiu et al.
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