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Brazilian green propolis-containing toothpaste with a well-balanced kaempferide/betuletol ratio enhances oral health and reduces specific harmful bacteria, thus offering a natural boost for oral hygiene.
Recent research issued in the “Journal of Ethnopharmacology” has explored the usefulness of adding Brazilian green propolis (BGP) to toothpaste to enhance oral health. Propolis, a resin collected by bees, has long been valued in traditional medicine for its antiviral, antibacterial, anti-inflammatory, and anti-tumor properties. However, its practical effectiveness in combating periodontal disease has not been thoroughly investigated. To address this gap, Shigeru Amano and other researchers carried out a study to explore the influence of BGP on oral health.
In this randomized, controlled, paired crossover study, 48 volunteers (24 males, 24 females, aged 18-40 years) were split into two groups. The BGP group received toothpaste containing BGP, while the placebo group received toothpaste without BGP. Over two weeks, researchers assessed plaque index (PI) and gingival index (GI) and measured periodontal pathogens on the tongue. They also identified antibacterial compounds in the BGP toothpaste using advanced analytical techniques.
The BGP toothpaste, containing 0.0347 w/v% propolis, showed a substantial reduction in PI scores (but not in the GI score) when compared to the placebo. Additionally, there was a decrease in the ratios of Porphyromonas gingivalis/Total bacteria, Fusobacterium nucleatum/Total bacteria, and Aggregatibacter actinomycetemcomitans/Total bacteria (p < 0.05). However, no vital change was witnessed in the ratio of Streptococcus salivarius/Total bacteria.
The effect sizes for Porphyromonas gingivalis, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans were 0.360, 0.556, and 0.164, respectively. Key antibacterial compounds in BGP encompassed a mix of Kaempferide and Betuletol. Hence, propolis toothpaste with an ideal kaempferide/betuletol ratio effectively improves oral microbiota. These findings support the clinical utility of BGP toothpaste in maintaining oral health and preventing periodontal illness.
Journal of Ethnopharmacology
Efficacy of toothpaste containing Brazilian green propolis extracts with an optimal kaempferide/betuletol ratio for improving oral microbiota: A randomized, controlled, paired crossover study
Shigeru Amano et al.
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