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Given the potential impact on quality of life due to premature ovarian insufficiency, healthcare providers should proactively discuss sexual health with women diagnosed with POI to improve overall well-being and mitigate its effect on sexual function.
Women with premature ovarian insufficiency (POI) face significant challenges in sexual function compared to those without the condition, according to recent research in Maturitas Journal.
Disruption of ovarian function before 40 years of age in women is known as POI or premature menopause. It is often linked with mood disorders and sexual dysfunction. However, despite its impact, high-quality evidence on how POI affects sexual function has been lacking—until now.
The comprehensive systematic review and meta-analysis was published after examining several online databases until January 2023 to shed light on this issue. The study investigated the data from 10 studies, with 352 women with POI participating in the meta-analysis.
The findings were clear: women with POI described reduced sexual function compared to control women. The overall effect size was noteworthy, with a medium Hedges' g effect size of -0.72, representing a noticeable difference in favor of the control group. When focusing on women using systemic hormone replacement therapy, the effect size was even greater (Hedges' g effect size of -0.82), underscoring a stronger impact on sexual function in those not undergoing hormone treatment.
Maturitas
Sexual function in women with premature ovarian insufficiency (POI): Systematic review and meta-analysis
Charissa van Zwol-Janssens et al.
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