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Feasibility and acceptability of Dextrose prolotherapy for symptomatic knee osteoarthritis, Pilot-level quality improvement project

Feasibility and acceptability of Dextrose prolotherapy for symptomatic knee osteoarthritis, Pilot-level quality improvement project Feasibility and acceptability of Dextrose prolotherapy for symptomatic knee osteoarthritis, Pilot-level quality improvement project
Feasibility and acceptability of Dextrose prolotherapy for symptomatic knee osteoarthritis, Pilot-level quality improvement project Feasibility and acceptability of Dextrose prolotherapy for symptomatic knee osteoarthritis, Pilot-level quality improvement project

What's new?

Prolotherapy infused with dextrose helps in improving performance and self reported measures in knee osteoarthritis patients.

The data from a study by Rabago D et al. revealed that prolotherapy in a primary care clinic is feasible and acceptable, as issued in 'The Journal of Alternative and Complementary Medicine'. Limited nonsurgical treatment options are available for knee osteoarthritis (KOA).

Prolotherapy is an injection-based method for chronic KOA pain; the health plan coverage is restricted, owing to an access barrier. Recently, a local health plan considered the coverage for prolotherapy for KOA, but uptake and treatment response in routine care are still undisclosed. The study authors performed a pilot-level quality improvement (QI) project to determine the feasibility, acceptability, and effects of prolotherapy for painful KOA in the primary care setting.This QI prospective case series had invitation letters sent to the symptomatic KOA patients with a primary care provider whose health plan had prolotherapy. The primary care patients with KOA were given intra- and extra-articular prolotherapy injections. A total of six prolotherapy sessions was given to patients.

The primary outcome measures comprised of feasibility having the response rate to an invitation to utilise prolotherapy. The acceptability was determined in the patient having adherence to, and satisfaction with, three or more prolotherapy sessions. The secondary outcomes comprised of survey-based (the Western Ontario McMaster University Osteoarthritis Index, WOMAC, 0-100; EuroQOL 5-D). The treadmill gait analysis, function (30-sec chair stand, 4 × 10 m walk, 9-step stair-climb), total activity (using accelerometer) and the preferred walking speed were objectively examined.

The outcome analysis (paired t-test) was according to the protocol, differentiating the follow-up and baseline outcome data at ∼eight months.Total 39 patients were invited out of which 11 responded and seven patients (with age 59.6 ± 9.3 years, six females) received 5.0 ± 1.1 prolotherapy sessions with a high satisfaction rate. At 8.4 months, their WOMAC scores improved by 27.6 ± 19.5 points. In the 4 × 10 m walk, the functional testing improved by 8.0 ± 3.6 sec. No group differences were observed between the baseline and follow-up in chair stand, stair-climb, accelerometry, or gait outcomes. Five patients increased their preferred walking speed." Self-reported improvement is similar to that of the efficacy studies; office-based, objectively examined functional assessment can be performed." Further evaluation is warranted, noted the study authors.

Source:

The Journal of Alternative and Complementary Medicine

Article:

Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis: Feasibility, Acceptability, and Patient-Oriented Outcomes in a Pilot-Level Quality Improvement Project

Authors:

Rabago D et al.

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