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Hyaluronic acid can be an effective treatment for temporomandibular disorders, with positive outcomes in pain reduction, increased mouth opening, and fewer joint sounds.
A recent study published in the “Journal of Oral Rehabilitation” shared evidence of the potential of hyaluronic acid (HA) in managing temporomandibular disorder (TMD) symptoms using the diagnostic criteria for TMD. The aim was to determine whether HA could enhance treatment outcomes for TMD-affected patients.
Ten studies were included in this systematic review after searching various databases like PubMed, Embase, Web of Science, Cochrane Library, Scopus, ScienceDirect, PsycINFO and CINAHL for studies investigating HA’s efficacy. Extraction of data and quality examination were performed by two reviewers. The ROB-2 tool was utilized to determine the methodological quality of the studies.
HA illustrated remarkable efficiency in alleviating TMD symptoms, with notable improvements in pain reduction, increased mouth opening, and a decrease in joint sounds as opposed to the control group, suggesting its potential as a beneficial therapeutic option. Additionally, platelet-rich plasma (PRP) showed superior effectiveness than HA intervention in alleviating TMD symptoms. Few studies reported minor and transient adverse effects. The risk of bias was assessed as low across all included studies.
The addition of HA as a treatment option for TMD offered promising results, indicating a path towards more beneficial pain management strategies in dental practices. The differing effectiveness across studies emphasizes the importance of personalized therapy and vigilant monitoring for adverse effects. Additional research is prudent to refine protocols and better understand HA's long-term safety and usefulness in TMD management.
Journal of Oral Rehabilitation
Efficacy of hyaluronic acid in temporomandibular disorders evaluated with diagnostic criteria for temporomandibular disorders (DC/TMD)
Pankaj Kukreja et al.
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