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IV Iron sucrose offers faster haemoglobin and iron restoration, even in the third trimester for pregnancy-related anaemia.
A latest research published in ' National Journal of Physiology Pharmacy and Pharmacology ' aimed to compare the efficacy and safety of oral versus intravenous (IV) iron sucrose for iron-deficiency anaemia during gestation.
Savitha A. and colleagues conducted a prospective observational study with 60 pregnant women between 24 and 36 weeks of gestation, who had haemoglobin levels ranging from 7 to 10 g/dL. In the study, one group received Iron sucrose IV 200 mg in 100 mL of 0.9% saline over 15–20 minutes on alternate days. The other group took Ferrous ascorbate 200 mg orally daily for 4 weeks. The study participants were observed for alterations in laboratory values and adverse effects, if any.
Both groups in the study experienced increased haemoglobin levels, but the IV group showed a notably more significant improvement than the oral group. Additionally, other laboratory parameters also exhibited greater improvement in the IV group compared to the oral group.
Importantly, the IV group did not report any major side effects throughout the study period.
Administration of IV iron sucrose was more effective than oral in correcting anaemia during gestation, as concluded.
National Journal of Physiology Pharmacy and Pharmacology
Comparative study of oral iron and intravenous iron sucrose for the treatment of iron-deficiency anemia in pregnancy
Savitha A et al.
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