Categories
Change Password!
Reset Password!
Direct oral anticoagulants may increase bleeding during tooth extractions, but most episodes are mild and manageable, suggesting that temporary suspension of these medications isn't always necessary.
A new research indicated that direct oral anticoagulants (DOACs) may elevate the risk of bleeding during tooth extractions. This prospective cohort study, published in the “Dentistry Journal”, investigated intra-, peri-, and post-operative bleeding occurrences in patients (age > 18 years) undergoing dental extractions while on DOACs, addressing concerns about bleeding risks in this population.
In this non-randomized, single-center clinical trial with a 1-week follow-up duration, individuals requiring a minimum of one dental extraction were enrolled. At baseline, the volunteers were assigned to groups based on their cardiologist's administration regimen:
Overall, 49 volunteers were stratified by the specific medication received (8 with Dabigatran, 8 with Edoxaban, 16 with Apixaban, 17 with Rivaroxaban). Among them, 33 abstained from DOAC administration before the procedure. The enrolled subjects were categorized into subgroups based on the number of teeth extracted (≤3 or >3), the requirement for flap elevation, and whether osteotomy was performed. Bleeding was monitored during the procedure and at several intervals (at 20, 40, 60, and 80 minutes post-procedure, and daily for the first seven days after tooth extractions).
Those undergoing more than three extractions, flap elevation, or osteotomy had markedly raised bleeding rates. Rivaroxaban and Apixaban were linked to more frequent bleeding. Patients treated with DOACs had similar rates of intra-operative, peri-operative, and post-operative bleeding rates. However, the episodes observed were mild and easily manageable. Cessation of anticoagulants before the procedure exhibited no effect on bleeding after the operation.
Dentistry Journal
Direct Oral Anticoagulants and Bleeding Management Following Tooth Extractions—A Prospective Cohort Study
Rossana Izzetti et al.
Comments (0)