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Obesity and hypoalbuminemia are helpful to predict infections after elective total knee arthroplasty

Obesity and hypoalbuminemia are helpful to predict infections after elective total knee arthroplasty Obesity and hypoalbuminemia are helpful to predict infections after elective total knee arthroplasty
Obesity and hypoalbuminemia are helpful to predict infections after elective total knee arthroplasty Obesity and hypoalbuminemia are helpful to predict infections after elective total knee arthroplasty

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Gouty arthritis patient with class II obesity (BMI ≥ 30 kg/m2) and hypoalbuminemia (serum albumin < 3.5 g/dL) are more likely to suffer from peri-prosthetic joint infection where as patients with less BMI values are not prone to the same.

As per a recent study published in ‘Knee Surgery and Related Research’, hypoalbuminemia and obesity class II can be used as reliable biomarkers to predict peri-prosthetic joint infection following elective total knee arthroplasty (TKA), while low TLC, overweight, and obesity class I did not increase the risk of such issues.

This study by Sheryl Lok-Chi Man et al. identified the biomarkers of malnutrition in patients undertaking elective TKA that may further give way to adverse in-hospital postoperative complications.

All in all, 624 patients who undertook elective TKA were assessed. To study the associated complications, potential biomarkers of preoperative malnutrition, comprising total lymphocyte count (TLC < 1500 cells/mm3), hypoalbuminemia (serum albumin < 3.5 g/dL), and BMI, were examined. As a result, obesity class I, low TLC, hypoalbuminemia, overweight and obesity class II was observed in 44.5%, 33.4%, 26.9%, 14.8% and 2.72% patients, correspondingly. Patients with hypoalbuminemia or being in obesity class II (BMI ≥ 30.0 kg/m2) with gouty arthritis were most likely to have peri-prosthetic joint infection considering the logistic regression analysis.

Source:

Knee Surgery and Related Research

Article:

Hypoalbuminemia and obesity class II are reliable predictors of peri-prosthetic joint infection in patient undergoing elective total knee arthroplasty

Authors:

Sheryl Lok-Chi Man et al.

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