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Preemptive use of NSAIDs is effective and safe for postoperative analgesia in femoroacetabular impingement patients receiving hip arthroscopy.
Compared to postoperative use, commencing non-steroidal anti-inflammatory drugs (NSAIDs) prior to hip arthroscopy surgery offered short-term pain alleviation and raised patient satisfaction, while not triggering additional adverse effects in individuals with femoroacetabular impingement, as elucidated from a multicenter, randomized, controlled study.
The management of postoperative pain is pivotal for hip surgery. In this study, 204 femoroacetabular impingement people scheduled to undergo surgery of the hip were examined to see how preemptive NSAIDs impacted postoperative analgesia. Participants were then randomly allocated to one of two groups: preoperative (N = 103) or postoperative (N = 101). The preoperative group received NSAIDs from 24 hours prior to surgery to day 7 (D7) after surgery. The postoperative group received NSAIDs from 12 hours following surgery to D7 after surgery.
When compared to the postoperative group, pain at rest was decreased at D1 and D2, and pain at movement was lowered at D1, D2, and D3 in the preoperative group, but not at other time points. In comparison with the postoperative group, patient satisfaction raised at D1 and D3, but not at D7 in the preoperative group. In comparison to the postoperative group, the preoperative group ingested less pethidine at D3 and D7. At D7, first month, and third month, Harris hip scores were comparable between groups. The frequency of negative events was comparable between groups.
Additionally, subgroup analysis showed that pain intensity was not affected by the types of NSAID in both groups. Thus, the preoperative use of NSAIDs is beneficial for pain management in people undergoing hip arthroscopy surgery.
The Journal of Clinical Pharmacy and Therapeutics
Efficacy and safety of preoperative versus postoperative NSAIDs on pain relief in patients undergoing hip arthroscopy surgery: A multicentre, randomized, controlled trial
Wei Zhang MM et al.
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