Categories
Change Password!
Reset Password!
Higher body mass index shows a small, non-significant negative correlation with utility indexes, highlighting the multifactorial nature of HRQoL. Factors like age, smoking, and comorbidities more markedly contribute to shaping these outcomes.
The relationship between body mass index (BMI) and quality of life (QoL) is a critical aspect of understanding the broader health implications of obesity. Two pivotal weight loss intervention studies, SCALE and STEP 1, provided valuable data for assessing this correlation using health-related quality of life (HRQoL) metrics. Researchers aimed to quantify the effects of BMI changes on individuals' well-being.
Health utility values were derived by mapping the Short Form Health Survey 36-Item (SF-36) scores from SCALE and STEP 1 to the EuroQoL-5 Dimensions-3 Levels (EQ-5D-3L) utility index for the UK. This mapping was done via a validated algorithm. Additionally, SF-36 scores from STEP 1 were transformed into Short Form 6 Dimension (SF-6D) utilities for Portugal.
This transformation was done via the University of Sheffield's tools. To explore the correlation between baseline BMI and utility, multiple linear regression analyses were performed, adjusting for demographic and clinical variables.
An elevated baseline BMI was found to be linked with reduced HRQoL utility scores (EQ-5D-3L and SF-6D). However, this trend was non-significant when considering the full population studied. For BMI ranges between 30–40 kg/m², each additional BMI unit corresponded to a reduction of 0.0031 and 0.0041 in EQ-5D-3L scores for females and males, respectively, in SCALE. Similarly, STEP 1 showed reductions of 0.0047 and 0.0039 in EQ-5D-3L scores and 0.0020 and 0.0027 in SF-6D scores for females and males, respectively.
In individuals with obesity and comparable demographic and clinical profiles, even small increases in BMI (1 unit) were linked to subtle declines in utility indices. The maximum observed change was 0.005, emphasizing the measurable yet modest impact of BMI on QoL. Understanding the nuanced relationship between BMI and utility can guide healthcare professionals in designing more effective, patient-centric weight loss strategies.
Advances in Therapy
The Correlation Between Body Mass Index and Health-Related Quality of Life: Data from Two Weight Loss Intervention Studies
Pavol Kral et al.
Comments (0)