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The relationship of periodontitis (PD) with the prevalence of rheumatoid arthritis (RA) is still under debate.
Periodontitis (PD) is a
persistent inflammatory condition known for the demolition of the
tooth-supporting tissues like cementum, alveolar bone and periodontal-ligament.
The following study concluded that it has significant associations rheumatoid
arthritis etc. The RA patients with PD receiving non-surgical periodontal
treatment resulted in prominent improvements in the clinical outcomes for
RA.
The relationship of periodontitis
(PD) with the prevalence of rheumatoid arthritis (RA) is still under debate.
Hence, this study aimed to estimate their association and examine the impacts
of non-surgical periodontal therapy on RA.
Sixty-four patients were selected
and classified into four groups; 10 healthy controls (PD−RA−), 18 PD patients
(PD+RA−), 18 RA with PD patients (PD+RA+), and 18 RA patients (PD−RA+).
Rheumatologic and periodontal parameters were measured at baseline and one
month after the non-surgical periodontal treatment.
The RA patients showed comparable
periodontal status. However, Higher levels of erythrocyte sedimentation rate
(ESR), Disease Activity Score 28 (DAS28), C-reactive protein (CRP), and anti-cyclic
citrulline peptide antibody (ACPA) was found in PD+RA+ group as compared to
PD−RA+ group. Also, the PD+RA+ group showed improved rheumatologic parameters
following the non-surgical periodontal treatment.
The PD might lead to the RA progression,
while RA might have limited influence on stimulating the PD development.
Furthermore, RA patients with PD taking non-surgical periodontal treatment
appeared to have an exceptional improvement in the clinical result for
RA.
Med Sci Monit
Association of Periodontitis with Rheumatoid Arthritis and the Effect of Non-Surgical Periodontal Treatment on Disease Activity in Patients with Rheumatoid Arthritis
Xinyuan Zhao et al.
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