Investigation of H. pylori prevalence in people with dyspepsia

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Created On: 25/02/2022

A cross-sectional study was conducted to examine commonness of Helicobacter pylori (H. pylori) infection in people having dyspepsia.

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Key take away

The overall prevalence of H. pylori disease is high in people suffering from dyspepsia.

Background

A cross-sectional study was conducted to examine commonness of Helicobacter pylori (H. pylori) infection in people having dyspepsia.

Method

In this study, subjects (above 18 years of age) suffering from dyspepsia were analyzed. Using the H. pylori stool antigen test (HpSA) test, H. pylori infection was evaluated. In subjects with HpSA negative results, the serological test was performed. Notably, 70.1% of subjects were under 40 years of age and 55.1% were female.

Result

The use of alcohol, drug, smoking, and non-steroidal anti-inflammatory drugs (NSAIDs) in the subjects were 6.3%, 7.9%, 16.5%, and 39.4%, respectively. The highest symptom was abdominal pain (44.9%) and the lowest symptom was burp (22%). With the exception of association between age and positive serological outcomes, no profound association was reported between other variables.

According to the HpSA test, H. pylori infection was observed in 56.7% of subjects. On the basis of serological test, 29 subjects were found to be H. pylori-infected. The total number of subjects was 101, and the overall prevalence of H. pylori infection raised to 79.5%.

Conclusion

The overall H. pylori infection prevalence was high. Higher positive test for H. pylori is seen in women above the age of 40 years in HpSA test and males in serology test, higher education level, and in the existence of risk factors (NSAIDs, alcohol, smoking).