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This retrospective observational research aimed to study the outcomes of infertile couples who received restorative reproductive medicine (RRM) therapy.
This
study supports the use of restorative reproductive medicine for infertility.
Younger women aged less than 35 years and females with a body mass index
< 25 had higher chances of having a live birth.
This
retrospective observational research aimed to study the outcomes of infertile couples who
received restorative reproductive medicine (RRM) therapy.
A total of 370 infertile couples were treated by
2 family physicians specialized in RRM. A retrospective review of the couple’s
characteristics, diagnoses, treatments, and outcomes between 1989-2014 was
carried out. Kaplan-Meier analysis helped evaluate pregnancy and live birth. The aggregate
proportion with pregnancy or with live birth was compared with
the help of Fleming-Harrington and weighted Renyi test or the log-rank test.
The mean age of total couples starting the treatment for infertility was 34.8 years. The mean time trying to conceive before the use of RRM was 2.7 years, and 27% of the women had a previous live birth. Mean number of diagnoses per couple was 4.9.
Fertility tracking (80%); medicines to boost cervical mucus production (81%), medicines to promote ovulation (62%), or to maintain the luteal phase (75%); and transfer to female laparoscopy by gynecologists (46%), were the treatment components.
Overall,
the cumulative live birth rate at two years was 29%, which was considerably
higher for 34% of females under age 35 years and for 40% of women with a body
mass index less than 25. In addition, two sets of twins were found, and no
higher-order multiple pregnancies. Notably, 58 (92%) births occurred at term
out of a total of 63 births.
For infertile patients,
family physicians can suggest RRM therapy to find out the causes of infertility
and facilitate healthy full-term live births.
BMC Pregnancy and Childbirth
Restorative reproductive medicine for infertility in two family medicine clinics in New England, an observational study
Joseph B. Stanford et al.
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