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A study investigated the existing research on the role of platelet-rich fibrin (PRF) in boosting distal repositioning of the canine teeth.
The use of platelet-rich fibrin is effective in accelerating the distal movement of canine teeth, supporting its role in enhancing this process during the first two months.
A study investigated the existing research on the role of platelet-rich fibrin (PRF) in boosting distal repositioning of the canine teeth.
A comprehensive search was performed across Google Scholar, Cochrane Central, PubMed, and Scopus using relevant search terms. Utilizing the Cochrane risk of bias (RoB)-2 tool, an inspection of the bias risk within the studies was done. Bias in published studies was examined via a funnel plot.
For the quantitative evaluation, a random effects model was applied, with the projected effects of the intervention expressed as mean differences (MD) along and 95% confidence intervals (CI). The evidence certainty was explored via the Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Following the search, 11 studies were incorporated in the qualitative analysis, and 3 studies were incorporated in the quantitative synthesis.
In this systematic review, the majority of the research reported greater canine distal movement following PRF use. The overall pooled canine distal movement at 1, 2, 3, 4, and 5 months portrayed a markedly higher mean value in injectable PRF (p<0.00001; MD = 0.23; 95% CI: 0.14 to 0.32), with the most dramatic rise witnessed during the first and second months. The studies illustrated a moderate to low risk of bias. Evidence certainty was rated as moderate.
PRF may be incorporated into standard orthodontic care whenever accelerated canine tooth distal movement is needed.
Cureus
Effectiveness of Platelet Rich Fibrin in Accelerating Canine Distal Movement: A Systematic Review of Randomized Controlled Trials
Swati Singh et al.
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