Quality of life improvements with photobiomodulation in burning mouth syndrome

Photobiomodulation along with low-level laser therapy effectively improves burning mouth syndrome symptoms and enhances quality of life, contributing to the curtailment or cessation of previous medication use.

The aim of this prospective study was to evaluate the usefulness of prolonged photobiomodulation (PBM) with low-level laser therapy (LLLT) on burning mouth syndrome (BMS) patients in a real-world setting.

The study included adult patients suffering from persistent and recurrent burning sensation in the mouth, with or without dysesthesia or pain. Oral PBM was administered by irradiating the affected areas every two weeks over a 12-month period. Researchers assessed health-related quality of life using the EQ-5D-5L questionnaire, monitored patients' pharmacological profile, and used nonparametric statistical analysis to determine statistical significance.

Fifteen individuals completed the study, including 14 females and 1 male. Remarkable improvements were noted in self-care, usual activities, pain/discomfort, patients' self-reported health status, and depression/anxiety dimensions of the health-related quality of life questionnaire. Thirteen participants reported either suspending or reducing their medication intake for BMS.

PBM with LLLT improves patients’ quality of life and lessens BMS symptoms, which helps patients reduce or suspend their previous medicines. The innovative approach and promising results indicate a need for additional research.