This prospective assessment was carried out to explore the symptoms day by day for non-hospitalized healthcare workers testing negative and positive for COVID-19.
The prevalence of long-lasting
decreased sense of smell and taste is greatly elevated in mild COVID-19
patients. Also, this pattern is noted for dyspnea at a low level, however not
for sore throat, fever, cough, headache, or muscle pain.
This prospective assessment was
carried out to explore the symptoms day by day for non-hospitalized healthcare
workers testing negative and positive for COVID-19.
In this 90-day follow-up study, 630
negative-test and 210 positive-test participants were followed for up to 90
days following testing. Their daily reported SARS-CoV-2-associated symptoms
were evaluated graphically and via logistic regression.
During all 90 days, about 30% of COVID-positive and close to 0% of COVID-negative subjects witnessed a decreased sense of smell and taste (adjusted odds ratio 86.07). An initial 20% of COVID-positive people witnessed dyspnea that reduced to 5% after 30 days, without ever achieving the level of the COVID-negative people (adjusted odds ratio 6.88).
Among the positive-test subjects,
muscle pain, fever, cough, headache, and sore throat were temporarily more
prevalent. Following 30 days, no increases were witnessed. Females and people aged 45 years or older were more
vulnerable to the long-lasting symptoms of coronavirus infection.
In individuals with mild
coronavirus infection, the prevalence of long-lasting diminished sense of smell
and taste is considerably increased.
International Society for Infectious Diseases
Day-by-day symptoms following positive and negative PCR tests for SARS-CoV-2 in non-hospitalized healthcare workers: A 90-day follow-up study
Kent J Nielsen et al.
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