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The goal was to determine the global prevalence of female sexual dysfunction (FSD) in women with rheumatoid arthritis (RA) and explore the risk factors associated with FSD in this group.
Sexual dysfunction is more prevalent in women with rheumatoid arthritis, underscoring the need for clinicians to prioritize sexual health.
The goal was to determine the global prevalence of female sexual dysfunction (FSD) in women with rheumatoid arthritis (RA) and explore the risk factors associated with FSD in this group.
Databases like Embase, PubMed, Web of Science, and Cochrane Library were explored. Random-effects meta-analysis was used for calculating the pooled prevalence. For the assessment of study heterogeneity, Q and I² tests were used. For identifying the sources of heterogeneity, subgroup analyses and meta-regression were applied. The pooled prevalence of FSD in RA sufferers was calculated. Odds ratios (ORs) along with 95% confidence intervals (CIs) were employed to examine the link between FSD-associated risk factors and RA.
In this systematic review and meta-analysis, 13 studies involving 2327 volunteers were included. The pooled prevalence of FSD in RA-affected females was 49.1%. Women with RA were at a markedly higher risk of FSD when compared to healthy controls (OR, 3.10). Depression (OR, 1.42) and menopause (OR, 5.46) were identified as substantial risk factors for FSD in this group.
A significant association was reported between RA and the risk of FSD. Additionally, menopause and depression were strongly linked to FSD.
The Journal of Sexual Medicine
Prevalence and risk factors of sexual dysfunction in female participants with rheumatoid arthritis: a systematic review and meta-analysis
Jiaguo Huang et al.
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