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Supplement neurouridine is effective to treat low back pain

Supplement neurouridine is effective to treat low back pain Supplement neurouridine is effective to treat low back pain
Supplement neurouridine is effective to treat low back pain Supplement neurouridine is effective to treat low back pain

An open observational (MULTINEURO-1) trial was conducted on the safety and efficacy of elevated doses (150 mg) of uridine monophosphate  in combination with choline to treat individuals having low back pain.

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Key take away

Clinicians now would be able to use uridine monophosphate (high doses) in combination with choline (the supplement neurouridine) to treat patients with non-specific low back pain.

Background

An open observational (MULTINEURO-1) trial was conducted on the safety and efficacy of elevated doses (150 mg) of uridine monophosphate  in combination with choline to treat individuals having low back pain.

Method

The study recruited 50 patients suffering from non-specific low back pain. For evaluating the efficacy, the following scales were utilized: (a) the painDETECT questionnaire (PD-Q), (b) the Hospital Anxiety and Depression Scale (HADS), (c) Visual Analogue scale (VAS), (d) the Roland-Morris Low Back Pain and Disability Questionnaire (RMQ), and (e) the Pittsburgh Sleep Quality Index

Result

A greater decline in the pain intensity was noted in the main group than in the comparison group. The results of PD-Q illustrated a remarkable decline in the severity of the neuropathic component of pain in the treatment group. The RMQ revealed signs of improved functional status.

Conclusion

High doses of uridine monophosphate in combination with supplement neurouridine appear to yield satisfactory outcomes in patients with nonspecific acute low back pain.

Source:

Journal of Neurology and Psychiatry

Article:

[The results of an open observational study on multimodal effects of the efficacy and safety of supplement neurouridine in patients with nonspecific low back pain (MULTINEURO-1)]

Authors:

E Z Yakupov et al.

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