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While pulpectomy has long been the standard of care, its complexity and potential complications have prompted a shift toward modern, minimally invasive treatments like pulpotomy, which aim to preserve pulp vitality.
In pulpitis-affected patients, endosequence bio-ceramic root repair material offers superior pain reduction, periapical healing, and sensitivity improvement when compared to other pulpotomy agents.
While pulpectomy has long been the standard of care, its complexity and potential complications have prompted a shift toward modern, minimally invasive treatments like pulpotomy, which aim to preserve pulp vitality.
This randomized controlled trial delved into the comparative efficiency of four advanced pulpotomy agents in mature permanent molars, assessing their clinical and radiographic outcomes.
Overall, 80 people (aged 14–60 years) diagnosed with symptomatic irreversible pulpitis were recruited. Volunteers were randomly divided into 4 groups, each treated with one of the biomaterials: biodentine, mineral trioxide aggregate (MTA), bio-C repair, and endosequence bio-ceramic root repair material (BCRRM).
Pulpotomy procedures were carried out, with outcomes monitored at 24 hours, 1 week, 4 weeks, and at 3, 6, and 12 months. Clinical success was marked by the absence of tenderness, sensitivity, and pain. Using periapical index scoring system, the radiographic healing was determined.
The findings were striking. All groups experienced a dramatic decline in postoperative pain. Endosequence BCRRM emerged as the standout performer, delivering the most substantial pain relief at 24 hours, with prominent results at the 1% probability level, followed by bio-C repair, biodentine, and MTA. At 1 week, bio-C repair showed pain alleviation, though differences were statistically insignificant.
By 3, 6, and 12 months, all groups experienced complete pain resolution. Radiographically, endosequence BCRRM illustrated the most pronounced periapical healing at 1 year. The sensitivity to cold and hot stimuli markedly improved across all the groups, with endosequence BCRRM consistently outperforming its peers.
Endosequence BCRRM set a new benchmark in pulpotomy efficacy, outperforming its counterparts and underscoring the pivotal role of biomaterial choice in optimizing patient outcomes. These findings pave the way for further research to explore the long-term potential of innovative pulpotomy agents, aiming to redefine standards in minimally invasive endodontic care.
Journal of Conservative Dentistry and Endodontics
Comparative evaluation of various biomaterials as pulpotomy agents in molars with symptomatic irreversible pulpitis: A randomized single-blinded single-center control trial
Vidushi Gilhotra et al.
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