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To explore the association between air pollution exposure and the development of dermatitis or eczema and food allergies during the first decade of life.
Implementing policies to reduce air pollution may help decrease the occurrence and long-term persistence of peanut allergies.
To explore the association between air pollution exposure and the development of dermatitis or eczema and food allergies during the first decade of life.
The HealthNuts, a population-based longitudinal study, followed a cohort of 1-year-old infants through ages 4, 6, and 10 years, assessing the impact of annual average particulate matter (PM2.5) and nitrogen dioxide (NO2) exposures at geocoded residential addresses. Eczema was parent-reported, while oral food challenges to peanut, egg and sesame helped determine food allergy. Adjusted odds ratios for associations were estimated using multilevel logistic regression models.
Encounter to raised NO2 levels (less than 10 parts per billion [ppb]) at 1 year was associated with increased incidence of peanut allergy at age 1 and age 4. Increased NO2 exposure at age 6 led to a higher prevalence of peanut allergy at age 6. Similarly, higher PM2.5 exposure at age 1 was linked to peanut allergy at younger years of life (aged 4, 6 and 10 years) (Table 1).
Exposure to PM2.5 and NO2 during early life was linked to both the prevalence and prolonged peanut allergy symptoms.
The Journal of Allergy and Clinical Immunology
Air pollution is associated with persistent peanut allergy in the first 10 years
Diego J Lopez et al.
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